SCHEMBL258447

SCHEMBL258447

CCCCCC/C=C/C(=O)NCC(C)C

nearest known ligand 0.80

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 6/20 0.80
CNR1 P21554 4/20 0.80
EPHX1 P07099 1/20 0.51
PPARG P37231 2/20 0.50
PPARD Q03181 2/20 0.50
PPARA Q07869 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5553149 1.00 CNR2 (0.80) CNR2CNR1EPHX1PPARGPPARD
SCHEMBL1946504 1.00 CNR2 (0.80) CNR2CNR1EPHX1PPARGPPARD
SCHEMBL258448 1.00 CNR2 (0.80) CNR2CNR1EPHX1PPARGPPARD
SCHEMBL20883258 1.00 CNR2 (0.80) CNR2CNR1EPHX1PPARGPPARD
SCHEMBL20883283 1.00 CNR2 (0.80) CNR2CNR1EPHX1PPARGPPARD
SCHEMBL5553152 1.00 CNR2 (0.80) CNR2CNR1EPHX1PPARGPPARD
SCHEMBL1030756 1.00 CNR2 (0.80) CNR2CNR1EPHX1PPARGPPARD
SCHEMBL4205215 0.95 CNR2 (0.73) CNR2CNR1PPARGPPARDPPARA
SCHEMBL29406024 0.90 CNR2 (0.66) CNR2CNR1PPARGPPARDPPARA
SCHEMBL2262688 0.89 CNR2 (1.00) CNR2CNR1PPARGPPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250066320-A1 Active Ingredients with Sialagogue and Tingling/Fizzy Effect, and Preparations Containing Same SYMRISE AG (DE) 2025-02-27 US claimed
EP-3969163-B1 BIODEGRADABLE POLYUREA/POLYURETHANE MICROCAPSULES SYMRISE AG (DE) 2024-12-11 EP claimed
EP-4452941-A1 ACTIVE INGREDIENTS WITH SIALAGOGUE AND TINGLING/FIZZY EFFECT, AND PREPARATIONS CONTAINING SAME Symrise AG (DE) 2024-10-30 EP claimed
EP-1517880-B1 PRODUCTION OF CIS-PELLITORIN AND USE AS A FLAVOURING SYMRISE AG (DE) 2011-01-05 EP claimed
EP-4192614-B1 PROCESS FOR THE PREPARATION OF MICROCAPSULES SYMRISE AG (DE) 2026-05-06 EP disclosed
US-20250144589-A1 Method for Producing Microcapsules SYMRISE AG (DE) 2025-05-08 US disclosed
US-20250066320-A1 Active Ingredients with Sialagogue and Tingling/Fizzy Effect, and Preparations Containing Same SYMRISE AG (DE) 2025-02-27 US disclosed
EP-4472763-A1 METHOD FOR PRODUCING MICROCAPSULES Symrise AG (DE) 2024-12-11 EP disclosed
EP-3969163-B1 BIODEGRADABLE POLYUREA/POLYURETHANE MICROCAPSULES SYMRISE AG (DE) 2024-12-11 EP disclosed
EP-4452941-A1 ACTIVE INGREDIENTS WITH SIALAGOGUE AND TINGLING/FIZZY EFFECT, AND PREPARATIONS CONTAINING SAME Symrise AG (DE) 2024-10-30 EP disclosed
US-20240293790-A1 Biodegradable Polyurea/Polyurethane Microcapsules SYMRISE AG (DE) 2024-09-05 US disclosed
EP-4378575-A1 POLYUREA/POLYURETHANE MICROCAPSULES Symrise AG (DE) 2024-06-05 EP disclosed
WO-2006032664-A1 USE OF ISOEUGENOL METHYL ETHER AS AN AGENT AGAINST BAD BREATH SYMRISE GMBH & CO. KG (DE) 2006-03-30 WO disclosed
US-20050244561-A1 Carvone acetals used as flavourings SYMRISE GMBH & CO. KG (DE) 2005-11-03 US disclosed
US-20050234132-A1 Production of cis-pellitorin and use as a flavouring SYMRISE AG (DE) 2005-10-20 US disclosed
US-20050208084-A1 Use of alkylamidomandelates as flavourings SYMRISE GMBH & CO. KG (DE) 2005-09-22 US disclosed
US-20040241312-A1 Use of 2E,4E-decadienoic acid isobutylamide for imparting a salivation inducing effect to a foodstuff, an oral hygiene preparation or a gourmet or snack preparation; preparation by amidating a dodecadienoate with isobutylamine SYMRISE AG (DE) 2004-12-02 US disclosed
US-6673756-B2 MULTILAYER; CUTTING, JOINING UNDER PRESSURE SYMRISE GMBH & CO. KG (DE) 2004-01-06 US disclosed
US-20030152682-A1 Use of ferulic acid amides as flavor compounds SYMRISE AG (DE) 2003-08-14 US disclosed
US-20020173436-A1 Multilayer; cutting, joining under pressure SYMRISE GMBH & CO. KG (DE) 2002-11-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050234132-A1 Production of cis-pellitorin and use as a flavouring NISCH, CYP8B1, DLAT CNR2 2674/4885CNR1 3549/4885EPHX1 896/4885
US-20050208084-A1 Use of alkylamidomandelates as flavourings HNMT, TAS2R7, PNMT CNR2 83/4885CNR1 158/4885EPHX1 1804/4885
US-20250066320-A1 Active Ingredients with Sialagogue and Tingling/Fizzy Effect, and Preparations Containing Same TAS2R5, TAS2R7, TAS2R8 CNR2 3211/4885CNR1 2662/4885EPHX1 2617/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.