SCHEMBL25847386

SCHEMBL25847386

CCCCC/C=C\C/C=C\C/C=C\CCCCCCC(=O)NC(C)C

nearest known ligand 0.91

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.72
KMT2A Q03164 2/20 0.72
FAAH O00519 1/20 0.72
MAPK1 P28482 1/20 0.72
ALDH1A1 P00352 2/20 0.69
SMN1; SMN2 Q16637 1/20 0.69
KCNK3 O14649 1/20 0.69
THRB P10828 1/20 0.69
CNR2 P34972 1/20 0.69
BLM P54132 1/20 0.69
TDP1 Q9NUW8 1/20 0.69
SLC6A5 Q9Y345 1/20 0.69
CNR1 P21554 2/20 0.63
HPGD P15428 1/20 0.62
TRPV1 Q8NER1 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22758117 1.00 MEN1 (0.72) MEN1KMT2AFAAHMAPK1ALDH1A1
SCHEMBL6534948 0.95 CNR2 (0.76) ALDH1A1SMN1; SMN2KCNK3THRBCNR2
SCHEMBL6903752 0.95 FAAH (0.79) MEN1KMT2AFAAHMAPK1ALDH1A1
SCHEMBL1456866 0.95 FAAH (0.79) MEN1KMT2AFAAHMAPK1ALDH1A1
SCHEMBL1456449 0.95 FAAH (0.79) MEN1KMT2AFAAHMAPK1ALDH1A1
SCHEMBL5682652 0.89 ALDH1A1 (0.68) MEN1KMT2AALDH1A1SMN1; SMN2KCNK3
SCHEMBL5145799 0.89 ALDH1A1 (0.68) MEN1KMT2AALDH1A1SMN1; SMN2KCNK3
SCHEMBL653624 0.89 ALDH1A1 (0.68) MEN1KMT2AALDH1A1SMN1; SMN2KCNK3
SCHEMBL11872018 0.89 ALDH1A1 (0.68) MEN1KMT2AALDH1A1SMN1; SMN2KCNK3
SCHEMBL15285515 0.87 SMN1; SMN2 (0.92) MEN1KMT2AFAAHALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS Arrowhead Pharmaceuticals, Inc. 2023-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS CPT1B, MUSK, MYLK2 MEN1 4753/4885KMT2A 1603/4885FAAH 2901/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.