Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 5/20 | 0.38 |
| ▸ | BACE1 | P56817 | 4/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22625398 | 0.92 | MAOB (0.42) | MAOBMAOATHRBSMN1; SMN2KDM4E | |
| SCHEMBL22625419 | 0.92 | MAOB (0.41) | MAOBMAOATHRBSMN1; SMN2KDM4E | |
| SCHEMBL22625198 | 0.91 | MAOB (0.42) | MAOBMAOATHRBSMN1; SMN2KDM4E | |
| SCHEMBL25848349 | 0.91 | MAOB (0.41) | MAOBMAOATHRBSMN1; SMN2KDM4E | |
| SCHEMBL22625269 | 0.90 | MAOB (0.40) | MAOBMAOATHRBSMN1; SMN2KDM4E | |
| SCHEMBL25848362 | 0.90 | MAOB (0.40) | MAOBMAOATHRBSMN1; SMN2KDM4E | |
| SCHEMBL25848306 | 0.89 | MAOB (0.42) | MAOBMAOATHRBSMN1; SMN2KDM4E | |
| SCHEMBL25848316 | 0.89 | THRB (0.35) | MAOBMAOATHRBSMN1; SMN2HPGD | |
| SCHEMBL25848542 | 0.88 | MAOB (0.44) | MAOBMAOATHRBSMN1; SMN2KDM4E | |
| SCHEMBL25848309 | 0.87 | NPC1 (0.44) | MAOBMAOASMN1; SMN2KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11702396-B2 | Hydrophobic compounds for optically active devices | Johnson & Johnson Surgical Vision, Inc. (US) | 2023-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11702396-B2 | Hydrophobic compounds for optically active devices | UACA, CRYZ, TRPA1 | MAOB 3207/4885MAOA 2922/4885THRB 3289/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.