Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.48 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25848334 | 0.89 | ALDH1A1 (0.53) | TSHRCYP2D6MEN1KMT2ARECQL | |
| SCHEMBL25848324 | 0.83 | TDP1 (0.56) | TSHRCYP2D6MEN1KMT2ARECQL | |
| SCHEMBL25882668 | 0.80 | TSHR (0.51) | TSHRCYP2D6NR1H2NR1H3TDP1 | |
| SCHEMBL10655904 | 0.79 | MEN1 (0.56) | MEN1KMT2ARECQLNR1H2NR1H3 | |
| SCHEMBL29950775 | 0.79 | TSHR (0.55) | TSHRCYP2D6MEN1KMT2ANR1H2 | |
| SCHEMBL18868169 | 0.78 | CYP2D6 (0.50) | CYP2D6MEN1KMT2ARECQLNR1H2 | |
| SCHEMBL9089453 | 0.77 | SIGMAR1 (0.46) | CYP2D6MEN1KMT2ARECQLNR1H2 | |
| SCHEMBL29150566 | 0.77 | HSD17B3 (0.47) | TSHRCYP2D6MEN1KMT2ARECQL | |
| SCHEMBL4854148 | 0.76 | PRKCI (0.55) | TSHRCYP2D6MEN1KMT2ARECQL | |
| SCHEMBL1822448 | 0.76 | PRKCI (0.60) | TSHRCYP2D6MEN1KMT2ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11701922-B2 | Metal or metal-plated reinforcement with sulfur polybenzoxazine-coated surface | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2023-07-18 | — | — | US | disclosed |