SCHEMBL25848334

SCHEMBL25848334

CCN(Cc1ccccc1O)c1cccc(N(CC)Cc2ccccc2O)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.53
CYP3A4 P08684 1/20 0.53
MEN1 O00255 3/20 0.51
KMT2A Q03164 3/20 0.51
RECQL P46063 1/20 0.51
MAPT P10636 3/20 0.47
EGFR P00533 1/20 0.47
LCK P06239 1/20 0.47
HPGD P15428 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
CYP2D6 P10635 1/20 0.46
NR1H2 P55055 1/20 0.46
NR1H3 Q13133 1/20 0.46
TSHR P16473 1/20 0.46
GAA P10253 1/20 0.41
MAPK1 P28482 1/20 0.41
HTT P42858 1/20 0.41
S1PR1 P21453 3/20 0.41
HTR1A P08908 1/20 0.41
HSPA5 P11021 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25848331 0.89 TSHR (0.58) ALDH1A1CYP3A4MEN1KMT2ARECQL
SCHEMBL25848337 0.83 ALDH1A1 (0.50) ALDH1A1CYP3A4MEN1KMT2ARECQL
SCHEMBL9089453 0.78 SIGMAR1 (0.46) ALDH1A1MEN1KMT2ARECQLMAPT
SCHEMBL11231117 0.77 TDP1 (0.49) ALDH1A1CYP3A4MEN1KMT2ARECQL
SCHEMBL25848324 0.77 TDP1 (0.56) ALDH1A1CYP3A4MEN1KMT2ARECQL
SCHEMBL8913957 0.75 HTR1A (0.49) ALDH1A1CYP3A4MEN1KMT2ARECQL
SCHEMBL3825706 0.75 HSPA5 (0.53) ALDH1A1CYP3A4MEN1KMT2ARECQL
SCHEMBL1574035 0.74 ALDH1A1 (0.71) ALDH1A1CYP3A4MEN1KMT2ARECQL
SCHEMBL14283533 0.74 TSHR (0.81) ALDH1A1CYP3A4KMT2AMAPTHPGD
SCHEMBL31038835 0.74 PRKCI (0.60) ALDH1A1MEN1KMT2ARECQLMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11701922-B2 Metal or metal-plated reinforcement with sulfur polybenzoxazine-coated surface COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2023-07-18 US disclosed