Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 5/20 | 0.34 |
| ▸ | TYR | P14679 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TERT | O14746 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.31 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.31 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18583391 | 0.84 | ALDH1A1 (0.56) | ALDH1A1ACHEERN1TYRTRIM24 | |
| SCHEMBL20473359 | 0.80 | ALDH1A1 (0.49) | ALDH1A1TSHRNPC1RAB9AERN1 | |
| SCHEMBL31068412 | 0.80 | ALDH1A1 (0.49) | ALDH1A1TSHRNPC1RAB9AERN1 | |
| SCHEMBL11080267 | 0.77 | ALDH1A1 (0.48) | ALDH1A1TSHRACHENPC1TDP1 | |
| SCHEMBL395733 | 0.77 | ALDH1A1 (0.48) | ALDH1A1ACHENPC1PKMRAB9A | |
| SCHEMBL20244667 | 0.74 | ALDH1A1 (0.53) | ALDH1A1ACHENPC1RAB9AL3MBTL1 | |
| SCHEMBL5479766 | 0.74 | ALDH1A1 (0.50) | ALDH1A1ACHETYRL3MBTL1KDM4E | |
| SCHEMBL4455438 | 0.73 | ALDH1A1 (0.54) | ALDH1A1ACHERAB9AL3MBTL1GAA | |
| SCHEMBL30772981 | 0.73 | ALDH1A1 (0.54) | ALDH1A1ACHERAB9AL3MBTL1GAA | |
| SCHEMBL8793789 | 0.73 | ALDH1A1 (0.42) | ALDH1A1ACHENPC1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11702396-B2 | Hydrophobic compounds for optically active devices | Johnson & Johnson Surgical Vision, Inc. (US) | 2023-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11702396-B2 | Hydrophobic compounds for optically active devices | UACA, CRYZ, TRPA1 | ALDH1A1 1851/4885TSHR 3882/4885ACHE 895/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.