SCHEMBL25848538

SCHEMBL25848538

CCCCC(F)(F)CCCO

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.55
LMNA P02545 2/20 0.52
ALDH1A1 P00352 2/20 0.52
HSD17B10 Q99714 2/20 0.52
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
TSHR P16473 2/20 0.52
CES2 O00748 3/20 0.35
LPAR1 Q92633 1/20 0.35
LPAR3 Q9UBY5 1/20 0.35
FAAH O00519 8/20 0.34
CES1 P23141 5/20 0.33
CYP1A2 P05177 1/20 0.33
FDPS P14324 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14831463 0.90 LMNA (0.62) SMN1; SMN2LMNAALDH1A1HSD17B10MEN1
SCHEMBL23015199 0.90 LMNA (0.62) SMN1; SMN2LMNAALDH1A1HSD17B10MEN1
SCHEMBL16845302 0.90 LMNA (0.62) SMN1; SMN2LMNAALDH1A1HSD17B10MEN1
SCHEMBL14830449 0.90 LMNA (0.62) SMN1; SMN2LMNAALDH1A1HSD17B10MEN1
SCHEMBL4023703 0.86 SMN1; SMN2 (0.37) SMN1; SMN2LMNAALDH1A1HSD17B10MEN1
SCHEMBL11685471 0.86 TSHR (0.40) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL20128921 0.81
SCHEMBL6085851 0.81
SCHEMBL11867732 0.80 TSHR (0.35) LMNAHSD17B10MEN1KMT2ATSHR
SCHEMBL21061177 0.80 LMNA (0.48) SMN1; SMN2LMNAALDH1A1HSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11702396-B2 Hydrophobic compounds for optically active devices Johnson & Johnson Surgical Vision, Inc. (US) 2023-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11702396-B2 Hydrophobic compounds for optically active devices UACA, CRYZ, TRPA1 SMN1; SMN2 4872/4885LMNA 2186/4885ALDH1A1 1851/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.