Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25705259 | 0.86 | NPSR1 (0.49) | PKMSMN1; SMN2ALDH1A1AOX1NPSR1 | |
| SCHEMBL13109368 | 0.83 | LPAR1 (0.39) | THRBPKMSMN1; SMN2TSHRAOX1 | |
| SCHEMBL258550 | 0.81 | AOX1 (0.38) | THRBPKMSMN1; SMN2TSHRAOX1 | |
| SCHEMBL16920471 | 0.80 | THRB (0.58) | THRBPKMSMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL19944676 | 0.80 | THRB (0.58) | THRBPKMSMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL25705277 | 0.80 | NPSR1 (0.50) | SMN1; SMN2ALDH1A1AOX1NPSR1USP2 | |
| SCHEMBL29475861 | 0.79 | THRB (0.56) | THRBPKMSMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL13498169 | 0.79 | PKM (0.54) | PKMSMN1; SMN2TSHRALDH1A1HSD17B10 | |
| SCHEMBL28615728 | 0.79 | NPSR1 (0.45) | PKMSMN1; SMN2ALDH1A1AOX1NPSR1 | |
| SCHEMBL258565 | 0.78 | THRB (0.41) | THRBPKMSMN1; SMN2TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8063123-B2 | Phosphorus-containing mixtures, a process for their preparation and their use | CLARIANT FINANCE (BVI) LIMITED (VG) | 2011-11-22 | — | — | US | disclosed |
| US-20070225414-A1 | Phosphorus-containing mixtures, a process for their preparation and their use | CLARIANT INTERNATIONAL LTD | 2007-09-27 | — | — | US | disclosed |