Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOX1 | Q06278 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL258565 | 0.96 | THRB (0.41) | AOX1THRBPOLBAPEX1HTT | |
| SCHEMBL258572 | 0.93 | POLB (0.41) | AOX1THRBPOLBAPEX1HTT | |
| SCHEMBL13109399 | 0.85 | AOX1 (0.36) | AOX1POLBAPEX1HTTTDP1 | |
| SCHEMBL25705259 | 0.85 | NPSR1 (0.49) | AOX1POLBNPSR1CA2PKM | |
| SCHEMBL13109382 | 0.83 | LPAR1 (0.38) | AOX1POLBNPSR1PKMSMN1; SMN2 | |
| SCHEMBL13109386 | 0.81 | AOX1 (0.34) | AOX1POLBNPSR1PKMSMN1; SMN2 | |
| SCHEMBL717904 | 0.81 | THRB (0.44) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL17263538 | 0.81 | KMT2A (0.54) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL258493 | 0.81 | THRB (0.50) | AOX1THRBTDP1NPSR1CA2 | |
| SCHEMBL13109393 | 0.80 | DGAT1 (0.34) | AOX1POLBNPSR1PKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8063123-B2 | Phosphorus-containing mixtures, a process for their preparation and their use | CLARIANT FINANCE (BVI) LIMITED (VG) | 2011-11-22 | — | — | US | disclosed |
| US-20070225414-A1 | Phosphorus-containing mixtures, a process for their preparation and their use | CLARIANT INTERNATIONAL LTD | 2007-09-27 | — | — | US | disclosed |