SCHEMBL25849617

SCHEMBL25849617

CC(C)N1/C(=C/C=C2C(=O)c3cc4ccccc4cc3C2=O)N(C)c2nc3ccccc3nc21

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ILF3 Q12906 1/20 0.34
RAB9A P51151 3/20 0.33
NPC1 O15118 2/20 0.33
HIF1A Q16665 1/20 0.33
MAPT P10636 8/20 0.33
ALDH1A1 P00352 5/20 0.33
SMN1; SMN2 Q16637 4/20 0.33
NFKB1 P19838 1/20 0.33
CASP3 P42574 1/20 0.33
NFKB2 Q00653 1/20 0.33
RELA Q04206 1/20 0.33
SENP8 Q96LD8 1/20 0.33
SENP7 Q9BQF6 1/20 0.33
SENP6 Q9GZR1 1/20 0.33
KDM4E B2RXH2 3/20 0.32
L3MBTL1 Q9Y468 3/20 0.32
LMNA P02545 2/20 0.32
MAPK1 P28482 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
PLIN1 O60240 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25849612 0.89 ILF3 (0.39) ILF3RAB9ANPC1HIF1AMAPT
SCHEMBL25849863 0.82 ELANE (0.44) RAB9ANPC1MAPTALDH1A1SMN1; SMN2
SCHEMBL25849601 0.81 ILF3 (0.34) ILF3RAB9ANPC1HIF1AMAPT
SCHEMBL25851059 0.81 MAPT (0.32) RAB9ANPC1HIF1AMAPTALDH1A1
SCHEMBL25849614 0.81 ILF3 (0.34) ILF3RAB9ANPC1HIF1AMAPT
SCHEMBL25849554 0.80 DPP4 (0.36) ILF3MAPTKMT2AMEN1APEX1
SCHEMBL25849608 0.78 ALDH1A1 (0.37) ILF3RAB9ANPC1MAPTALDH1A1
SCHEMBL25849603 0.77 ILF3 (0.32) ILF3MAPTALDH1A1SMN1; SMN2NFKB1
SCHEMBL25849609 0.77 MAPK14 (0.33) ILF3ALDH1A1KDM4EHTT
SCHEMBL25849623 0.77 MEN1 (0.37) ALDH1A1SMN1; SMN2KDM4EKMT2APKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230232713-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2023-07-20 US disclosed