Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | FASN | P49327 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25849676 | 0.69 | RIPK1 (0.32) | RIPK1NAMPTFASN | |
| SCHEMBL25848587 | 0.67 | RIPK1 (0.35) | RIPK1NAMPTFASN | |
| SCHEMBL25848676 | 0.66 | NAMPT (0.33) | RIPK1NAMPTFASN | |
| SCHEMBL25848673 | 0.61 | NAMPT (0.43) | RIPK1NAMPTFASN | |
| SCHEMBL20012496 | 0.60 | EPHX2 (0.41) | DPP8NAMPTFASN | |
| SCHEMBL17815833 | 0.59 | DPP8 (0.36) | RIPK1DPP8FASN | |
| SCHEMBL12767514 | 0.59 | HSD11B1 (0.49) | FASN | |
| SCHEMBL30920969 | 0.58 | FASN (0.44) | RIPK1NAMPTFASN | |
| SCHEMBL8485188 | 0.58 | FASN (0.44) | FASN | |
| SCHEMBL17282284 | 0.58 | USP2 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131122-A1 | FUSED RING-SUBSTITUTED SIX-MEMBERED HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2023-07-13 | — | — | WO | disclosed |