SCHEMBL25849799

SCHEMBL25849799

CN1/C(=C/C=C2C(=O)c3cc4ccccc4cc3C2=O)Sc2c1ccc1ccccc21

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD3 P35462 2/20 0.35
PRMT1 Q99873 5/20 0.34
DNMT1 P26358 1/20 0.33
ILF3 Q12906 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
HIF1A Q16665 1/20 0.32
MAPT P10636 4/20 0.32
MEN1 O00255 3/20 0.32
KMT2A Q03164 3/20 0.32
KDM4E B2RXH2 2/20 0.32
CYP11B1 P15538 1/20 0.32
CYP11B2 P19099 1/20 0.32
PRMT5 O14744 1/20 0.31
CARM1 Q86X55 1/20 0.31
PRMT8 Q9NR22 1/20 0.31
GSK3A P49840 1/20 0.31
GSK3B P49841 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25850041 0.90 DRD3 (0.41) DRD3PRMT1DNMT1MAPTMEN1
SCHEMBL25851513 0.89 DNMT1 (0.34) DRD3PRMT1DNMT1
SCHEMBL25849806 0.81 ALDH1A1 (0.33) PRMT1DNMT1MAPTMEN1KMT2A
SCHEMBL25849797 0.80 ALDH1A1 (0.46) DRD3CYP1A2CYP2C19MAPTMEN1
SCHEMBL25849795 0.72 MAPT (0.45) DRD3PRMT1MAPTMEN1KMT2A
SCHEMBL12776610 0.72 DRD3 (0.48) DRD3CYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL23337592 0.70 ILF3 (0.39) ILF3HIF1AMAPTMEN1KMT2A
SCHEMBL10843290 0.70 RAB9A (0.47) PRMT1CYP1A2CYP2C9CYP2C19MAPT
SCHEMBL12776573 0.69 DRD3 (0.52) DRD3PRMT1CYP1A2CYP2D6CYP2C9
SCHEMBL25850890 0.69 DNMT1 (0.32) DNMT1MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230232713-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2023-07-20 US disclosed