SCHEMBL25849806

SCHEMBL25849806

CN1/C(=C/C=C2\C(=O)c3ccccc3C2=C(C#N)C#N)Sc2c1ccc1ccccc21

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
MAPT P10636 2/20 0.33
EGFR P00533 1/20 0.33
DNMT1 P26358 1/20 0.32
MEN1 O00255 1/20 0.30
POLB P06746 1/20 0.30
KMT2A Q03164 1/20 0.30
PRMT1 Q99873 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25850890 0.89 DNMT1 (0.32) ALDH1A1MAPTDNMT1
SCHEMBL25849804 0.81 MAPT (0.41) ALDH1A1MAPTMEN1POLBKMT2A
SCHEMBL25849799 0.81 DRD3 (0.35) ALDH1A1MAPTDNMT1MEN1KMT2A
SCHEMBL25850041 0.79 DRD3 (0.41) ALDH1A1MAPTDNMT1MEN1POLB
SCHEMBL25849800 0.78 KMT2A (0.42) ALDH1A1MAPTEGFRMEN1POLB
SCHEMBL25851513 0.78 DNMT1 (0.34) DNMT1PRMT1
SCHEMBL25850882 0.73 PRMT1 (0.34) ALDH1A1MAPTDNMT1MEN1POLB
SCHEMBL12721871 0.71 MCL1 (0.36) ALDH1A1MAPTDNMT1MEN1POLB
SCHEMBL12217153 0.69 MAPT (0.61) ALDH1A1MAPTMEN1POLBKMT2A
SCHEMBL25165432 0.69 PRMT1 (0.31) MAPTMEN1POLBKMT2APRMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230232713-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2023-07-20 US disclosed