SCHEMBL2584981

SCHEMBL2584981

CCc1cc(S(=O)(=O)c2cc(C)c(O)c(CC)c2)cc(C)c1O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.37
ALOX5 P09917 1/20 0.37
PTGS1 P23219 1/20 0.37
PTGS2 P35354 1/20 0.37
ESR1 P03372 3/20 0.36
ESR2 Q92731 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36
POLB P06746 1/20 0.36
KMT2A Q03164 3/20 0.36
MAPT P10636 2/20 0.36
MEN1 O00255 2/20 0.36
ALDH1A1 P00352 2/20 0.36
GABRA1 P14867 1/20 0.35
GABRB2 P47870 1/20 0.35
KDM4E B2RXH2 1/20 0.35
USP2 O75604 1/20 0.35
CYTH2 Q99418 1/20 0.35
CA1 P00915 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10024007 0.90 RAPGEF4 (0.50) ESR1POLBKMT2AMAPTMEN1
SCHEMBL258494 0.87 GABRA1 (0.46) CYP1A2CYP3A4CYP2C9POLBMAPT
SCHEMBL10024008 0.86 ING2 (0.42) SHBGALOX5PTGS1PTGS2ESR1
SCHEMBL10887675 0.86 SHBG (0.53) SHBGPOLBKMT2AMAPTMEN1
SCHEMBL10887676 0.86 SHBG (0.53) SHBGPOLBKMT2AMAPTMEN1
SCHEMBL359985 0.83 CA1 (0.50) ALOX5PTGS1PTGS2ESR1ESR2
SCHEMBL142565 0.83 CA1 (0.50) ALOX5PTGS1PTGS2ESR1ESR2
SCHEMBL4061816 0.78 RAPGEF4 (0.41) SHBGESR1ESR2ALDH1A1CA1
SCHEMBL26254558 0.78 GFER (0.38) ESR2POLBKMT2AMAPTMEN1
SCHEMBL8403864 0.76 ALDH1A1 (0.46) CYP3A4CYP2C9POLBMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011134674-A1 IMPROVED LIGHT DIFFUSING COMPOSITION STYRON EUROPE GMBH (CH) 2011-11-03 WO disclosed
CN-1215103-C Process for the preparation of polycarbonates DOW GLOBAL TECHNOLOGIES CO (US) 2005-08-17 CN disclosed
EP-1274762-B1 POLYCARBONATE PREPARATION PROCESS DOW GLOBAL TECHNOLOGIES INC (US) 2005-05-11 EP disclosed
CN-1158352-C Polycarbonate formulation and carrier for semiconductor wafers that is opaque to certain light wavelengths ͨ�õ�����˾ 2004-07-21 CN disclosed
CN-1420901-A Polycarbonate preparation process DOW GLOBAL TECHNOLOGIES CO (US) 2003-05-28 CN disclosed
EP-0870791-B1 Reducing ionic impurities content in polycarbonate resins GEN ELECTRIC (US) 2003-02-05 EP disclosed
EP-1274762-A1 POLYCARBONATE PREPARATION PROCESS THE DOW CHEMICAL COMPANY (US) 2003-01-15 EP disclosed
WO-2001077204-A1 POLYCARBONATE PREPARATION PROCESS DOW GLOBAL TECHNOLOGIES INC. (US) 2001-10-18 WO disclosed
US-6225436-B1 REACTING PHOSGENE AND DIHYDRIC PHENOL; ADDING ACYL HALIDE; ADDING A CHAIN TERMINATOR TO THE REACTION MIXTURE; COMPLETING POLYMERIZATION REACTION THE DOW CHEMICAL COMPANY 2001-05-01 US disclosed
EP-0941268-A1 POLYCARBONATES THE DOW CHEMICAL COMPANY (US) 1999-09-15 EP disclosed
US-4156769-A Process for making polycarbonates using 1,1-dimethyl urea compounds as the catalysts THE DOW CHEMICAL COMPANY (US) 1979-05-29 US disclosed
US-4111910-A POLYCARBONATES HAVING CARBAMATE TERMINAL GROUPS THE DOW CHEMICAL COMPANY (US) 1978-09-05 US disclosed
US-4101519-A MOLECULAR WEIGHT REDUCTION, TERTIARY AMINE CATALYST GENERAL ELECTRIC COMPANY (US) 1978-07-18 US disclosed
US-4100139-A Polycarbonates incorporating epihalohydrin residues THE DOW CHEMICAL COMPANY (US) 1978-07-11 US disclosed
US-4092288-A WITH A PHOSPHINE AND AN EPOXY COMPOUND GENERAL ELECTRIC COMPANY (US) 1978-05-30 US disclosed
US-4076686-A EPOXY ETHANE OR CYCLOHEXANE COMPOUNDS WITH A PHOSPHITE GENERAL ELECTRIC COMPANY (US) 1978-02-28 US disclosed
US-4059566-A Process for controlling the molecular weight of polycarbonates using ammonia or ammonia compounds THE DOW CHEMICAL COMPANY (US) 1977-11-22 US disclosed
US-4055544-A Process for making polycarbonates using ammonia or ammonia compounds as the catalysts THE DOW CHEMICAL COMPANY (US) 1977-10-25 US disclosed
US-4020045-A METALLIC SULFITES THE DOW CHEMICAL COMPANY (US) 1977-04-26 US disclosed
US-3992357-A THERMOPLASTIC THE DOW CHEMICAL COMPANY (US) 1976-11-16 US disclosed