SCHEMBL25849820

SCHEMBL25849820

CCN1C(=O)C2=C(c3ccc(N(C)c4ccccc4)cc3)N(CC)C(=O)C2=C1c1ccc(N(C)c2ccccc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 3/20 0.42
NR1H3 Q13133 3/20 0.42
ALDH1A1 P00352 6/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
ALOX15 P16050 1/20 0.41
GSK3B P49841 2/20 0.38
CRHBP P24387 1/20 0.38
CRHR2 Q13324 1/20 0.38
CHKA P35790 2/20 0.37
NR3C2 P08235 1/20 0.36
HSD17B10 Q99714 1/20 0.35
HPGD P15428 2/20 0.35
LMNA P02545 3/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
NPSR1 Q6W5P4 2/20 0.34
S1PR4 O95977 1/20 0.34
HSP90AA1 P07900 1/20 0.34
S1PR1 P21453 1/20 0.34
MAPK1 P28482 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18327868 0.91 NR1H2 (0.44) NR1H2NR1H3ALDH1A1MEN1KMT2A
SCHEMBL10050134 0.88 NR1H2 (0.46) NR1H2NR1H3ALDH1A1MEN1KMT2A
SCHEMBL15353831 0.86 NR1H2 (0.47) NR1H2NR1H3ALDH1A1MEN1KMT2A
SCHEMBL23954161 0.84 ALDH1A1 (0.38) NR1H2NR1H3ALDH1A1MEN1KMT2A
SCHEMBL9835835 0.84 NR1H2 (0.56) NR1H2NR1H3ALDH1A1MEN1KMT2A
SCHEMBL12391805 0.80 CDC25A (0.40) ALDH1A1
SCHEMBL10050138 0.79 SIGMAR1 (0.36) NR1H2NR1H3ALDH1A1MEN1KMT2A
SCHEMBL10050136 0.78 NR1H2 (0.35) NR1H2NR1H3ALDH1A1MEN1KMT2A
SCHEMBL25849817 0.77 GAA (0.40) NR1H2NR1H3ALDH1A1MEN1KMT2A
SCHEMBL10050137 0.75 NR1H2 (0.47) NR1H2NR1H3ALDH1A1GSK3BHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230232713-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2023-07-20 US disclosed