SCHEMBL9835835

SCHEMBL9835835

CCN1C(=O)C2=C(c3ccccc3)N(CC)C(=O)C2=C1c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 5/20 0.56
NR1H3 Q13133 5/20 0.56
ALDH1A1 P00352 3/20 0.40
MAPK1 P28482 2/20 0.40
MAPT P10636 2/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
AGTR1 P30556 1/20 0.40
THRB P10828 1/20 0.40
CTNNB1 P35222 1/20 0.40
RECQL P46063 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
LMNA P02545 2/20 0.40
ADORA3 P0DMS8 1/20 0.40
CYP1B1 Q16678 1/20 0.39
LCK P06239 1/20 0.37
GMNN O75496 1/20 0.37
THPO P40225 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15353831 0.88 NR1H2 (0.47) NR1H2NR1H3ALDH1A1MAPK1MAPT
SCHEMBL10050134 0.87 NR1H2 (0.46) NR1H2NR1H3ALDH1A1MAPK1MAPT
SCHEMBL18327868 0.86 NR1H2 (0.44) NR1H2NR1H3ALDH1A1MAPK1MAPT
SCHEMBL25849820 0.84 NR1H2 (0.42) NR1H2NR1H3ALDH1A1MAPK1MAPT
SCHEMBL14560459 0.83 NR1H2 (0.69) NR1H2NR1H3ALDH1A1MAPK1MAPT
SCHEMBL9836829 0.82 NPC1 (0.49) NR1H2NR1H3ALDH1A1MAPTMEN1
SCHEMBL8568473 0.81 NR1H2 (0.61) NR1H2NR1H3ALDH1A1MAPK1MAPT
SCHEMBL16456162 0.81 SENP1 (0.39) NR1H2NR1H3ALDH1A1MAPTLMNA
SCHEMBL9837963 0.81 NR1H2 (0.50) NR1H2NR1H3ALDH1A1MAPTKMT2A
SCHEMBL7489174 0.80 NR1H2 (0.40) NR1H2NR1H3MAPTSMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9211510-B2 Method for producing nanoparticles by forced ultrathin film rotary processing M. TECHNIQUE CO., LTD. (JP) 2015-12-15 US disclosed
US-20110178199-A1 METHOD FOR PRODUCING ORGANIC COMPOUND AND ORGANIC COMPOUND OBTAINED BY THE METHOD M. TECHNIQUE CO., LTD. (JP) 2011-07-21 US disclosed
US-20100155310-A1 METHOD FOR PRODUCING NANOPARTICLES BY FORCED ULTRATHIN FILM ROTARY PROCESSING M. TECHNIQUE CO., LTD. (JP) 2010-06-24 US disclosed
US-20090156827-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS AND ORGANIC ELECTROLUMINESCENT ELEMENT TOYO INK MFG. CO., LTD. (JP) 2009-06-18 US disclosed
US-20090156827-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS AND ORGANIC ELECTROLUMINESCENT ELEMENT TOYO INK MFG. CO., LTD. (JP) 2009-06-18 US disclosed
EP-2025733-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ORGANIC ELECTROLUMINESCENCE ELEMENT TOYO INK MFG. CO., LTD. (JP) 2009-02-18 EP disclosed
EP-0133156-B1 1,4-DIKETOPYRROLO-(3,4-C) PYRROLES CIBA-GEIGY AG (CH) 1991-07-10 EP disclosed
US-4666455-A Compositions pigmented with N-substituted 1,4-diketopyrrolo-[3,4-c]-pyrroles CIBA-GEIGY CORPORATION (US) 1987-05-19 US disclosed
US-4585878-A N-substituted 1,4-diketopyrrolo-[3,4-c]-pyrroles CIBA-GEIGY CORPORATION (US) 1986-04-29 US disclosed
EP-0133156-A2 1,4-Diketopyrrolo-(3,4-c) pyrroles CIBA-GEIGY AG (CH) 1985-02-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090156827-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS AND ORGANIC ELECTROLUMINESCENT ELEMENT ELP1, ELAVL1, ELF3 NR1H2 1829/4885NR1H3 1235/4885ALDH1A1 1089/4885
US-20110178199-A1 METHOD FOR PRODUCING ORGANIC COMPOUND AND ORGANIC COMPOUND OBTAINED BY THE METHOD OR10J3, PORCN, ABCG2 NR1H2 1689/4885NR1H3 707/4885ALDH1A1 3191/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.