SCHEMBL25849863

SCHEMBL25849863

Cc1ccc2c(c1)C(=O)/C(=C/C=C1N(C(C)C)c3nc4ccccc4nc3N1C(C)C)C2=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.44
MAPT P10636 9/20 0.39
SMN1; SMN2 Q16637 6/20 0.39
RAB9A P51151 4/20 0.39
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39
TDO2 P48775 1/20 0.38
IDO2 Q6ZQW0 1/20 0.38
NR1I2 O75469 1/20 0.37
EGFR P00533 1/20 0.37
ADRA2A P08913 1/20 0.37
ADORA3 P0DMS8 1/20 0.37
TBXA2R P21731 1/20 0.37
PTGS2 P35354 1/20 0.37
OPRD1 P41143 1/20 0.37
PDE4D Q08499 1/20 0.37
ALDH1A1 P00352 7/20 0.36
KDM4E B2RXH2 5/20 0.36
POLB P06746 1/20 0.36
GAA P10253 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25851059 0.87 MAPT (0.32) MAPTSMN1; SMN2RAB9AALDH1A1KDM4E
SCHEMBL25849840 0.82 ELANE (0.43) ELANEMAPTSMN1; SMN2RAB9AMAOA
SCHEMBL25849860 0.82 ELANE (0.43) ELANEMAPTSMN1; SMN2RAB9AMAOA
SCHEMBL25849617 0.82 ILF3 (0.34) MAPTSMN1; SMN2RAB9AALDH1A1KDM4E
SCHEMBL25849846 0.80 ELANE (0.41) ELANEMAPTSMN1; SMN2RAB9AMAOA
SCHEMBL25849843 0.80 ELANE (0.41) ELANEMAPTSMN1; SMN2RAB9AMAOA
SCHEMBL25849822 0.80 ELANE (0.39) ELANEMAPTSMN1; SMN2RAB9AMAOA
SCHEMBL25849849 0.78 ELANE (0.40) ELANEMAPTSMN1; SMN2RAB9AMAOA
SCHEMBL25849852 0.78 ELANE (0.40) ELANEMAPTSMN1; SMN2RAB9AMAOA
SCHEMBL25849866 0.78 ALDH1A1 (0.41) ELANEMAPTSMN1; SMN2RAB9AMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230232713-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2023-07-20 US disclosed