SCHEMBL25849846

SCHEMBL25849846

Cc1ccc2c(c1)C(=O)/C(=C/C=C1N(c3c(C)cccc3C)c3nc4ccccc4nc3N1c1c(C)cccc1C)C2=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.41
MAPT P10636 10/20 0.37
SMN1; SMN2 Q16637 5/20 0.37
RAB9A P51151 4/20 0.37
MEN1 O00255 7/20 0.37
KMT2A Q03164 7/20 0.37
ALDH1A1 P00352 5/20 0.37
KDM4E B2RXH2 5/20 0.37
CASP1 P29466 4/20 0.37
CASP7 P55210 4/20 0.37
ALOX15 P16050 3/20 0.37
HSD17B10 Q99714 3/20 0.37
MAPK1 P28482 3/20 0.37
HTT P42858 3/20 0.37
USP2 O75604 2/20 0.37
POLB P06746 2/20 0.36
PKM P14618 2/20 0.36
GAA P10253 1/20 0.36
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25849843 0.93 ELANE (0.41) ELANEMAPTSMN1; SMN2RAB9AMEN1
SCHEMBL25849849 0.89 ELANE (0.40) ELANEMAPTSMN1; SMN2RAB9AMEN1
SCHEMBL25851011 0.89 MAPT (0.33) MAPTSMN1; SMN2RAB9AMEN1KMT2A
SCHEMBL25849852 0.89 ELANE (0.40) ELANEMAPTSMN1; SMN2RAB9AMEN1
SCHEMBL25849822 0.88 ELANE (0.39) ELANEMAPTSMN1; SMN2RAB9AMEN1
SCHEMBL25849840 0.86 ELANE (0.43) ELANEMAPTSMN1; SMN2RAB9AMEN1
SCHEMBL23338714 0.86 LMNA (0.34) MAPTSMN1; SMN2RAB9AMEN1KMT2A
SCHEMBL23338726 0.84 MAPT (0.33) MAPTSMN1; SMN2RAB9AMEN1KMT2A
SCHEMBL25849608 0.83 ALDH1A1 (0.37) MAPTSMN1; SMN2RAB9AMEN1KMT2A
SCHEMBL25849837 0.83 ANPEP (0.37) ELANEMAPTSMN1; SMN2RAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230232713-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2023-07-20 US disclosed