Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DBH | P09172 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | FLT1 | P17948 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | VEGFA | P15692 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20503881 | 0.90 | MAPK14 (0.40) | DBHMAPK14EGLN1ADORA2AMAPT | |
| SCHEMBL20504077 | 0.90 | MAPK14 (0.37) | DBHMAPK14EGLN1ADORA2AMAPT | |
| SCHEMBL25857254 | 0.90 | MAPT (0.42) | DBHMAPK14ADORA2AMAPTTP53 | |
| SCHEMBL20504056 | 0.86 | MAPK14 (0.40) | MAPK14ADORA2AMAPTTP53EGFR | |
| SCHEMBL20504129 | 0.86 | ADRA1D (0.46) | MAPK14ADORA2APOLBKMT2AL3MBTL1 | |
| SCHEMBL25852107 | 0.86 | EGLN1 (0.54) | DBHMAPK14EGLN1MAPTTHRB | |
| SCHEMBL20936157 | 0.83 | MAPK14 (0.58) | MAPK14ADORA2ATP53FLT1KDR | |
| SCHEMBL20503999 | 0.83 | P2RX3 (0.39) | MAPK14MAPTTP53 | |
| SCHEMBL20504128 | 0.82 | MAPK14 (0.40) | MAPK14 | |
| SCHEMBL25852271 | 0.81 | KMT2A (0.49) | MAPK14ADORA2AHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023135233-A1 | AZAINDOLE DERIVATIVES AND THEIR USE AS ERK KINASE INHIBITORS | AGV DISCOVERY (FR) | 2023-07-20 | — | — | WO | disclosed |
| EP-4212531-A1 | AZAINDOLE DERIVATIVES AND THEIR USE AS ERK KINASE INHIBITORS | AGV Discovery (FR) | 2023-07-19 | — | — | EP | disclosed |