Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 6/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | BMP1 | P13497 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21906568 | 0.84 | CA2 (0.61) | CA2CA1KMT2AALOX15BLM | |
| SCHEMBL25853764 | 0.84 | CA2 (0.61) | CA2CA1KMT2AALOX15BLM | |
| SCHEMBL8505667 | 0.82 | CA2 (0.56) | CA2CA1KMT2AALOX15BLM | |
| SCHEMBL19661172 | 0.82 | CA2 (0.56) | CA2CA1KMT2AALOX15BLM | |
| SCHEMBL25853752 | 0.81 | ALDH1A1 (0.43) | CA2CA1TSHRUSP2MAPK1 | |
| SCHEMBL723391 | 0.79 | FOLH1 (0.48) | CYP1A2HDAC8 | |
| SCHEMBL27543202 | 0.77 | TSHR (0.38) | CA2CA1TSHRUSP2MAPK1 | |
| SCHEMBL28048852 | 0.77 | TSHR (0.38) | CA2CA1TSHRUSP2MAPK1 | |
| SCHEMBL25141834 | 0.77 | ALOX15 (0.43) | CA2CA1KMT2AALOX15BLM | |
| SCHEMBL19192783 | 0.76 | CA2 (0.41) | CA2CA1KMT2AALOX15BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840881-A | ADDING A BRANCHED CYCLODEXTRIN-CARBOXYLIC ACID | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-11-24 | — | — | US | disclosed |