SCHEMBL25854602

SCHEMBL25854602

CCOC(=O)[C@@H](C)C1c2ccccc2OCC12CC2

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.38
MGAM O43451 1/20 0.38
AMY1A P0DUB6 1/20 0.38
SI P14410 1/20 0.38
MGAM2 Q2M2H8 1/20 0.38
KDM4E B2RXH2 4/20 0.38
ALDH1A1 P00352 4/20 0.38
MAPT P10636 3/20 0.38
APEX1 P27695 1/20 0.38
POLB P06746 3/20 0.37
RECQL P46063 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
L3MBTL1 Q9Y468 3/20 0.35
TSHR P16473 2/20 0.35
NPSR1 Q6W5P4 1/20 0.35
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
ALOX15 P16050 1/20 0.34
HSD17B10 Q99714 1/20 0.34
ATM Q13315 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25526257 0.81 ALDH1A1 (0.32) ALDH1A1ATM
SCHEMBL25854536 0.79 ACE (0.39) ALDH1A1MAPTL3MBTL1HSD17B10
SCHEMBL25854599 0.77 HTR2B (0.31)
SCHEMBL25854605 0.72 GAA (0.39) GAAMGAMAMY1ASIMGAM2
SCHEMBL11815677 0.68 ALDH1A1 (0.43) GAAKDM4EALDH1A1MAPTAPEX1
SCHEMBL22877299 0.68 CYP3A4 (0.43) GAAMGAMAMY1ASIMGAM2
SCHEMBL25854582 0.68 OPRM1 (0.36) GAAALDH1A1TDP1MEN1KMT2A
SCHEMBL25854871 0.67 GRM7 (0.35)
SCHEMBL6773566 0.66 ALDH1A1 (0.45) GAAMGAMAMY1ASIMGAM2
SCHEMBL29617345 0.66 CYP1A2 (0.45) KDM4EALDH1A1MAPTPOLBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230227437-A1 IMMUNOMODULATOR HITGEN INC (CN) 2023-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230227437-A1 IMMUNOMODULATOR IL17A, IL2, IL2RA GAA 2382/4885MGAM 2305/4885AMY1A 2947/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.