Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26429440 | 0.70 | CYP2D6 (0.40) | ALDH1A1LMNAHTR2BPSMB5 | |
| SCHEMBL25854602 | 0.68 | GAA (0.38) | ALDH1A1L3MBTL1TSHRPOLBKMT2A | |
| SCHEMBL26704688 | 0.68 | BCHE (0.40) | ALDH1A1LMNAL3MBTL1TSHRPOLB | |
| SCHEMBL22877253 | 0.67 | CYP3A4 (0.37) | CYP3A4ALDH1A1LMNAL3MBTL1TSHR | |
| SCHEMBL22877204 | 0.66 | POLB (0.40) | ALDH1A1LMNAPOLBGAAPSMB5 | |
| SCHEMBL22877375 | 0.66 | POLB (0.40) | ALDH1A1LMNAPOLBGAAPSMB5 | |
| SCHEMBL26429346 | 0.66 | CYP2D6 (0.39) | CYP3A4ALDH1A1HTR2BPSMB5 | |
| SCHEMBL28438106 | 0.66 | L3MBTL1 (0.49) | CYP3A4L3MBTL1TSHRPOLBKMT2A | |
| SCHEMBL22877403 | 0.65 | LTB4R (0.55) | PSMB5 | |
| SCHEMBL26429444 | 0.65 | ALDH1A1 (0.41) | CYP3A4ALDH1A1LMNAL3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11639340-B2 | Substituted chromanes, analogs thereof, and methods of use and synthesis | NORTHWESTERN UNIVERSITY (US) | 2023-05-02 | — | — | US | disclosed |
| US-20210009547-A1 | SUBSTITUTED CHROMANES, ANALOGS THEREOF, AND METHODS OF USE AND SYNTHESIS | NORTHWESTERN UNIVERSITY (US) | 2021-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210009547-A1 | SUBSTITUTED CHROMANES, ANALOGS THEREOF, AND METHODS OF USE AND SYNTHESIS | TYR, ME1, PNPO | CYP3A4 12/4885ALDH1A1 444/4885LMNA 2033/4885 |
| US-11639340-B2 | Substituted chromanes, analogs thereof, and methods of use and synthesis | TYR, ME1, PNPO | CYP3A4 12/4885ALDH1A1 444/4885LMNA 2033/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.