SCHEMBL2585571

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2488943	0.91	MAPT (0.40)	DRD2MAPTDRD4DRD3L3MBTL1
	SCHEMBL2490987	0.85	DRD4 (0.36)	DRD2MAPTDRD4DRD3L3MBTL1
	SCHEMBL2492433	0.85	ALDH1A1 (0.39)	HTR1AHTR7ADORA2BTP53HSD17B10
	SCHEMBL2491400	0.85	LMNA (0.42)	DRD2MAPTDRD3L3MBTL1LMNA
	SCHEMBL2491739	0.83	KDM4E (0.41)	L3MBTL1TP53SMN1; SMN2
	SCHEMBL2531189	0.82	CHKA (0.44)	KMT2AMEN1HTR1AHTR7HSD17B10
	SCHEMBL1136308	0.78	MAOB (0.39)	MAPTL3MBTL1GAA
	SCHEMBL2492254	0.76	MAOB (0.37)	GAA
	SCHEMBL1136167	0.75	MAOB (0.39)	L3MBTL1GAADCTPP1
	SCHEMBL2492562	0.72	ALDH1A1 (0.39)	MAPTLMNAKMT2AMEN1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.