Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | NCF1 | P14598 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24480582 | 0.86 | HRH3 (0.38) | HRH3CACNA2D1CACNA1BCACNB1 | |
| SCHEMBL22520701 | 0.84 | CACNA2D1 (0.36) | HRH3CACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL25621909 | 0.83 | OPRL1 (0.34) | CACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL25856190 | 0.82 | ACHE (0.42) | CACNA2D1CACNA1BCACNB1CACNA1CNCF1 | |
| SCHEMBL24480864 | 0.81 | NCF1 (0.32) | CACNA2D1CACNA1BCACNB1CACNA1CNCF1 | |
| SCHEMBL25122598 | 0.80 | CACNA2D1 (0.39) | HRH3CACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL25621906 | 0.80 | CACNA2D1 (0.32) | CACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL25026717 | 0.80 | HRH3 (0.41) | HRH3 | |
| SCHEMBL10092712 | 0.80 | CACNA2D1 (0.43) | HRH3CACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL27307184 | 0.79 | OPRM1 (0.38) | HRH3CACNA2D1CACNA1BCACNB1CACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131167-A1 | COMPOUND FOR INHIBITING AND DEGRADING IRAK4, AND PHARMACEUTICAL COMPOSITION AND PHARMACEUTICAL APPLICATION THEREOF | 海思科医药集团股份有限公司 | 2023-07-13 | — | — | WO | disclosed |