Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.49 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.33 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24480750 | 0.87 | ACHE (0.49) | ACHECARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL25856482 | 0.83 | ACHE (0.30) | ACHE | |
| SCHEMBL26748266 | 0.77 | ACHE (0.57) | ACHECARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL16388002 | 0.76 | KDM4E (0.37) | ACHECARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL25565670 | 0.74 | ACHE (0.59) | ACHECARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL23983253 | 0.74 | ACHE (0.59) | ACHECARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL25856484 | 0.73 | ACHE (0.53) | ACHECARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL24480753 | 0.73 | ACHE (0.45) | ACHECARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL25856483 | 0.73 | OPRL1 (0.39) | ACHEPOLB | |
| SCHEMBL12714592 | 0.73 | CHRM5 (0.39) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131167-A1 | COMPOUND FOR INHIBITING AND DEGRADING IRAK4, AND PHARMACEUTICAL COMPOSITION AND PHARMACEUTICAL APPLICATION THEREOF | 海思科医药集团股份有限公司 | 2023-07-13 | — | — | WO | disclosed |