Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25815809 | 0.89 | HTR6 (0.40) | HTR6HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL26507722 | 0.85 | CHRM5 (0.46) | HTR6SMN1; SMN2GBA1 | |
| SCHEMBL24480854 | 0.83 | HTR6 (0.33) | HTR6HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL24480695 | 0.83 | ACHE (0.43) | — | |
| SCHEMBL2547787 | 0.78 | CHRM5 (0.39) | HTR6HPGDKMT2ASMN1; SMN2GBA1 | |
| SCHEMBL25103854 | 0.77 | KMT2A (0.37) | HTR6HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL24480693 | 0.77 | GBA1 (0.47) | HTR6HPGDKMT2ASMN1; SMN2GBA1 | |
| SCHEMBL24033622 | 0.76 | JAK2 (0.35) | — | |
| SCHEMBL24032937 | 0.76 | JAK2 (0.35) | — | |
| SCHEMBL25856130 | 0.76 | ACHE (0.46) | GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131167-A1 | COMPOUND FOR INHIBITING AND DEGRADING IRAK4, AND PHARMACEUTICAL COMPOSITION AND PHARMACEUTICAL APPLICATION THEREOF | 海思科医药集团股份有限公司 | 2023-07-13 | — | — | WO | disclosed |