Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24480753 | 0.79 | ACHE (0.45) | ACHEPOLBKDM4E | |
| SCHEMBL13247999 | 0.78 | ACHE (0.62) | ACHEPOLBKDM4EHRH3 | |
| SCHEMBL24480750 | 0.74 | ACHE (0.49) | ACHEPOLBHRH3 | |
| SCHEMBL24480218 | 0.72 | ACHE (0.50) | ACHEPOLBKDM4EHRH3 | |
| SCHEMBL24480610 | 0.72 | ACHE (0.53) | ACHEKDM4E | |
| SCHEMBL26748266 | 0.71 | ACHE (0.57) | ACHEPOLBKDM4EHRH3 | |
| SCHEMBL25027129 | 0.71 | ACHE (0.53) | ACHEPOLBKDM4E | |
| SCHEMBL25856194 | 0.71 | ACHE (0.49) | ACHEPOLBHRH3 | |
| SCHEMBL11919193 | 0.70 | KDM4E (0.50) | ACHEPOLBKDM4EHRH3 | |
| SCHEMBL25856202 | 0.70 | ACHE (0.47) | ACHEPOLBKDM4EHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131167-A1 | COMPOUND FOR INHIBITING AND DEGRADING IRAK4, AND PHARMACEUTICAL COMPOSITION AND PHARMACEUTICAL APPLICATION THEREOF | 海思科医药集团股份有限公司 | 2023-07-13 | — | — | WO | disclosed |