Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.47 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23558440 | 0.88 | CASP3 (0.48) | NPC1SMN1; SMN2RAB9AMAPTMEN1 | |
| SCHEMBL30355400 | 0.86 | SMN1; SMN2 (0.60) | NPC1SMN1; SMN2RAB9ANPSR1HSD17B10 | |
| SCHEMBL23524244 | 0.86 | SMN1; SMN2 (0.60) | NPC1SMN1; SMN2RAB9ANPSR1HSD17B10 | |
| SCHEMBL25856984 | 0.83 | NPC1 (0.54) | NPC1SMN1; SMN2RAB9AMAPTMEN1 | |
| SCHEMBL25856927 | 0.82 | PKM (0.56) | NPC1SMN1; SMN2RAB9AMAPTMEN1 | |
| SCHEMBL25856639 | 0.81 | HCAR3 (0.44) | NPC1SMN1; SMN2RAB9AMAPTMEN1 | |
| SCHEMBL23524293 | 0.80 | NPC1 (0.51) | NPC1SMN1; SMN2RAB9AMAPTMEN1 | |
| SCHEMBL30355631 | 0.80 | NPC1 (0.51) | NPC1SMN1; SMN2RAB9AMAPTMEN1 | |
| SCHEMBL25856926 | 0.79 | ENPP3 (0.47) | NPC1SMN1; SMN2RAB9AMAPTMEN1 | |
| SCHEMBL23524055 | 0.78 | NPC1 (0.48) | NPC1SMN1; SMN2RAB9AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230234946-A1 | COMPOUNDS FOR MODULATING S1P1 ACTIVITY AND METHODS OF USING THE SAME | TREVENA, INC. | 2023-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230234946-A1 | COMPOUNDS FOR MODULATING S1P1 ACTIVITY AND METHODS OF USING THE SAME | S1PR1, S1PR2, S1PR3 | NPC1 301/4885SMN1; SMN2 1320/4885RAB9A 3056/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.