SCHEMBL25857043

SCHEMBL25857043

N/C(=N\C(=O)NCc1ccccc1)NCCN1C(=O)C2C3C=CC(O3)C2C1=O

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.52
OPRM1 P35372 1/20 0.46
OPRD1 P41143 1/20 0.46
OPRK1 P41145 1/20 0.46
PKM P14618 1/20 0.45
LMNA P02545 2/20 0.42
ATM Q13315 1/20 0.38
KDM4E B2RXH2 1/20 0.37
TAAR1 Q96RJ0 1/20 0.37
TPSAB1 Q15661 1/20 0.37
TPSD1 Q9BZJ3 1/20 0.37
TPSG1 Q9NRR2 1/20 0.37
CASP1 P29466 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
HSD17B10 Q99714 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24746658 0.96 ALDH1A1 (0.52) ALDH1A1OPRM1OPRD1OPRK1PKM
SCHEMBL24746894 0.86 ALDH1A1 (0.51) ALDH1A1OPRM1OPRD1OPRK1PKM
SCHEMBL25857068 0.86 ALDH1A1 (0.46) ALDH1A1OPRM1OPRD1OPRK1LMNA
SCHEMBL25857121 0.85 ALDH1A1 (0.52) ALDH1A1OPRM1OPRD1OPRK1PKM
SCHEMBL24746660 0.84 ALDH1A1 (0.51) ALDH1A1OPRM1OPRD1OPRK1PKM
SCHEMBL25857056 0.82 ALDH1A1 (0.46) ALDH1A1OPRM1OPRD1OPRK1LMNA
SCHEMBL24748578 0.79 ALDH1A1 (0.47) ALDH1A1OPRM1OPRD1OPRK1PKM
SCHEMBL24746656 0.78 ALDH1A1 (0.45) ALDH1A1OPRM1OPRD1OPRK1PKM
SCHEMBL22100053 0.78 PKM (0.49) ALDH1A1OPRM1OPRD1OPRK1PKM
SCHEMBL24748568 0.77 ALDH1A1 (0.42) ALDH1A1OPRM1OPRD1OPRK1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11801228-B2 Modified guanidine-containing polymers for biologic delivery THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) 2023-10-31 US disclosed
US-20230225982-A1 MODIFIED GUANIDINE-CONTAINING POLYMERS FOR BIOLOGIC DELIVERY THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) 2023-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230225982-A1 MODIFIED GUANIDINE-CONTAINING POLYMERS FOR BIOLOGIC DELIVERY GMPS, RNMT, GUCY1A1 ALDH1A1 1829/4885OPRM1 2522/4885OPRD1 3897/4885
US-11801228-B2 Modified guanidine-containing polymers for biologic delivery GMPS, RNMT, GUCY1A1 ALDH1A1 1829/4885OPRM1 2522/4885OPRD1 3897/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.