Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.35 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.35 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25857056 | 0.96 | ALDH1A1 (0.46) | ALDH1A1LMNAMEN1KMT2AELANE | |
| SCHEMBL25857077 | 0.89 | ALDH1A1 (0.41) | ALDH1A1LMNAMEN1KMT2AELANE | |
| SCHEMBL25857050 | 0.87 | ALDH1A1 (0.43) | ALDH1A1LMNAMEN1KMT2AELANE | |
| SCHEMBL25857062 | 0.87 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2ATPSAB1TPSD1 | |
| SCHEMBL25857043 | 0.86 | ALDH1A1 (0.52) | ALDH1A1LMNATPSAB1TPSD1TPSG1 | |
| SCHEMBL25857060 | 0.85 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2ASMN1; SMN2OPRM1 | |
| SCHEMBL24746658 | 0.82 | ALDH1A1 (0.52) | ALDH1A1LMNATPSAB1TPSD1TPSG1 | |
| SCHEMBL25857078 | 0.79 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL24746998 | 0.79 | ALDH1A1 (0.38) | ALDH1A1LMNAELANETPSAB1TPSD1 | |
| SCHEMBL25857058 | 0.78 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2AOPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11801228-B2 | Modified guanidine-containing polymers for biologic delivery | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) | 2023-10-31 | — | — | US | disclosed |
| US-20230225982-A1 | MODIFIED GUANIDINE-CONTAINING POLYMERS FOR BIOLOGIC DELIVERY | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) | 2023-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230225982-A1 | MODIFIED GUANIDINE-CONTAINING POLYMERS FOR BIOLOGIC DELIVERY | GMPS, RNMT, GUCY1A1 | ALDH1A1 1829/4885LMNA 2545/4885MEN1 2661/4885 |
| US-11801228-B2 | Modified guanidine-containing polymers for biologic delivery | GMPS, RNMT, GUCY1A1 | ALDH1A1 1829/4885LMNA 2545/4885MEN1 2661/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.