SCHEMBL25857058

SCHEMBL25857058

C=CC1OC(C=C)C2C(=O)N(CCNC(=O)/N=C(\N)Nc3ncccn3)C(=O)C12

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.37
MEN1 O00255 1/20 0.37
HTT P42858 1/20 0.37
KMT2A Q03164 1/20 0.37
OPRM1 P35372 1/20 0.30
OPRD1 P41143 1/20 0.30
OPRK1 P41145 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25857080 0.91 ALDH1A1 (0.35) ALDH1A1MEN1HTTKMT2A
SCHEMBL25857071 0.89 MEN1 (0.35) ALDH1A1MEN1HTTKMT2A
SCHEMBL24746662 0.86 ALDH1A1 (0.41) ALDH1A1MEN1HTTKMT2AOPRM1
SCHEMBL25857060 0.85 ALDH1A1 (0.45) ALDH1A1MEN1HTTKMT2AOPRM1
SCHEMBL24746990 0.85 ALDH1A1 (0.39) ALDH1A1MEN1HTTKMT2AOPRM1
SCHEMBL25857056 0.80 ALDH1A1 (0.46) ALDH1A1MEN1HTTKMT2AOPRM1
SCHEMBL25857062 0.79 ALDH1A1 (0.45) ALDH1A1MEN1HTTKMT2A
SCHEMBL25857078 0.79 ALDH1A1 (0.40) ALDH1A1MEN1HTTKMT2A
SCHEMBL25857068 0.78 ALDH1A1 (0.46) ALDH1A1MEN1HTTKMT2AOPRM1
SCHEMBL25857073 0.74 ALDH1A1 (0.42) ALDH1A1MEN1HTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11801228-B2 Modified guanidine-containing polymers for biologic delivery THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) 2023-10-31 US disclosed
US-20230225982-A1 MODIFIED GUANIDINE-CONTAINING POLYMERS FOR BIOLOGIC DELIVERY THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) 2023-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230225982-A1 MODIFIED GUANIDINE-CONTAINING POLYMERS FOR BIOLOGIC DELIVERY GMPS, RNMT, GUCY1A1 ALDH1A1 1829/4885MEN1 2661/4885HTT 898/4885
US-11801228-B2 Modified guanidine-containing polymers for biologic delivery GMPS, RNMT, GUCY1A1 ALDH1A1 1829/4885MEN1 2661/4885HTT 898/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.