Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.48 |
| ▸ | HRH1 | P35367 | 2/20 | 0.48 |
| ▸ | HTR2B | P41595 | 2/20 | 0.48 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | PCTP | Q9UKL6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18037986 | 0.91 | SLC2A1 (0.61) | SLC2A1KMT2AMCHR1ADRA2AHRH1 | |
| SCHEMBL26503313 | 0.85 | MCHR1 (0.46) | SLC2A1KMT2AMCHR1ADRA2AHRH1 | |
| SCHEMBL23761729 | 0.81 | SLC2A1 (0.68) | SLC2A1KMT2ATGM2NPC1RAB9A | |
| SCHEMBL23761730 | 0.81 | SLC2A1 (0.68) | SLC2A1KMT2ATGM2NPC1RAB9A | |
| SCHEMBL25858229 | 0.80 | DNM2 (0.45) | SLC2A1KMT2AMCHR1NPC1RAB9A | |
| SCHEMBL25858259 | 0.79 | BLM (0.52) | SLC2A1KMT2ANPC1RAB9ABLM | |
| SCHEMBL19476884 | 0.79 | SLC2A1 (0.80) | SLC2A1KMT2AMCHR1ADRA2AHRH1 | |
| SCHEMBL25858213 | 0.78 | KMT2A (0.45) | KMT2ANPC1RAB9ABLMCNR1 | |
| SCHEMBL18037960 | 0.77 | NPC1 (0.47) | SLC2A1KMT2AMCHR1ADRA2AHRH1 | |
| SCHEMBL17985484 | 0.77 | ADRA2A (0.47) | SLC2A1KMT2AMCHR1ADRA2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230271926-A1 | INHIBITION OF OLIG2 ACTIVITY | Curtana Pharmaceuticals, Inc. | 2023-08-31 | — | — | US | disclosed |
| US-11691951-B2 | Inhibition of Olig2 activity | Curtana Pharmaceuticals, Inc. (US) | 2023-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11691951-B2 | Inhibition of Olig2 activity | GLI2, ING2, GMFG | SLC2A1 4252/4885KMT2A 501/4885MCHR1 4146/4885 |
| US-20230271926-A1 | INHIBITION OF OLIG2 ACTIVITY | GLI2, ING2, GMFG | SLC2A1 4252/4885KMT2A 501/4885MCHR1 4146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.