SCHEMBL25858228

SCHEMBL25858228

CC1(C)c2ccccc2-c2cc(Br)c3ccccc3c21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HKDC1 Q2TB90 1/20 0.38
PGR P06401 8/20 0.36
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
ALDH1A1 P00352 2/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32
PDK2 Q15119 2/20 0.32
MLNR O43193 1/20 0.31
NR1I2 O75469 1/20 0.31
CHRM2 P08172 1/20 0.31
ADRB1 P08588 1/20 0.31
HTR1A P08908 1/20 0.31
ADRA2A P08913 1/20 0.31
CHRM1 P11229 1/20 0.31
DRD2 P14416 1/20 0.31
ADRA2B P18089 1/20 0.31
ADRA2C P18825 1/20 0.31
CHRM3 P20309 1/20 0.31
DRD1 P21728 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16683879 0.85 PDK2 (0.39) HKDC1PGRCYP2D6CYP2C19ALDH1A1
SCHEMBL28598699 0.85 CYP1A2 (0.35) HKDC1PGRALDH1A1CYP1A2PDK2
SCHEMBL30589363 0.85 CYP1A2 (0.35) HKDC1PGRALDH1A1CYP1A2PDK2
SCHEMBL3756278 0.81 HKDC1 (0.33) HKDC1CYP2D6CYP2C19ALDH1A1CYP1A2
SCHEMBL28394446 0.78 PGR (0.38) PGRPDK2MAPT
SCHEMBL13002032 0.77 PGR (0.37) PGRPDK2MLNRNR1I2CHRM2
SCHEMBL19838518 0.77 DHFR (0.41) HKDC1CYP2D6CYP2C19ALDH1A1CYP1A2
SCHEMBL19077639 0.76 ALOX5 (0.31)
SCHEMBL29518351 0.76 PDK2 (0.38) HKDC1PGRCYP2D6CYP2C19ALDH1A1
SCHEMBL10010551 0.76 PDK2 (0.38) HKDC1PGRCYP2D6CYP2C19ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11711973-B2 Organic electronic device DUK SAN NEOLUX CO., LTD. (KR) 2023-07-25 US disclosed
US-11711973-B2 Organic electronic device DUK SAN NEOLUX CO., LTD. (KR) 2023-07-25 US disclosed