Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PROKR1 | Q8TCW9 | 3/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1188522 | 0.81 | GAA (0.38) | — | |
| SCHEMBL25859784 | 0.79 | CYP11B1 (0.33) | PROKR1 | |
| SCHEMBL2649829 | 0.75 | ALDH1A1 (0.36) | — | |
| SCHEMBL24982207 | 0.75 | SMN1; SMN2 (0.38) | — | |
| SCHEMBL24574595 | 0.75 | PDE10A (0.38) | PDE10A | |
| SCHEMBL1188150 | 0.74 | TDP1 (0.43) | PDE10A | |
| SCHEMBL29919389 | 0.74 | TDP1 (0.43) | PDE10A | |
| SCHEMBL31314265 | 0.73 | L3MBTL1 (0.36) | NPC1TSHRRAB9A | |
| SCHEMBL25255553 | 0.71 | IL1B (0.53) | — | |
| SCHEMBL25303027 | 0.71 | IL1B (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131277-A1 | NLRP3 INFLAMMASOME INHIBITOR AND USES THEREOF | 药捷安康(南京)科技股份有限公司 | 2023-07-13 | — | — | WO | disclosed |