Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.30 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25858265 | 0.79 | NPC1 (0.32) | PROKR1 | |
| SCHEMBL24574591 | 0.75 | PSMB5 (0.35) | PSMB5 | |
| SCHEMBL21745681 | 0.72 | PSMB5 (0.33) | PSMB5 | |
| SCHEMBL24784943 | 0.69 | NOS3 (0.33) | NOS3NOS2NUDT1CHRNB2CHRNA4 | |
| SCHEMBL24784939 | 0.69 | NCF1 (0.38) | CYP11B1PSMB5NOS3NOS2 | |
| SCHEMBL24740776 | 0.68 | PSMB5 (0.44) | CYP11B2PSMB5 | |
| SCHEMBL25778898 | 0.65 | NOS3 (0.31) | NOS3NOS2 | |
| SCHEMBL21017387 | 0.64 | GLS (0.46) | CYP11B1PSMB5 | |
| SCHEMBL24186202 | 0.63 | — | — | |
| SCHEMBL20810663 | 0.63 | KCNH2 (0.49) | CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131277-A1 | NLRP3 INFLAMMASOME INHIBITOR AND USES THEREOF | 药捷安康(南京)科技股份有限公司 | 2023-07-13 | — | — | WO | disclosed |