Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31314309 | 0.83 | — | — | |
| SCHEMBL25858367 | 0.83 | — | — | |
| SCHEMBL25858440 | 0.82 | ALDH1A1 (0.35) | — | |
| SCHEMBL31314201 | 0.82 | CACNA2D1 (0.31) | — | |
| SCHEMBL31314299 | 0.80 | GABRG2 (0.31) | GABRG2GABRB3GABRA5 | |
| SCHEMBL25860910 | 0.80 | NCF1 (0.33) | — | |
| SCHEMBL25299853 | 0.78 | EHMT2 (0.37) | — | |
| SCHEMBL31197274 | 0.78 | EHMT2 (0.37) | — | |
| SCHEMBL25299854 | 0.78 | EHMT2 (0.37) | — | |
| SCHEMBL25859894 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131277-A1 | NLRP3 INFLAMMASOME INHIBITOR AND USES THEREOF | 药捷安康(南京)科技股份有限公司 | 2023-07-13 | — | — | WO | disclosed |