Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.47 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.45 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CMA1 | P23946 | 2/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29359776 | 1.00 | EPHX1 (0.47) | EPHX1DPP8DPP9DPP7MEN1 | |
| Hydrochloric Acid SCHEMBL4087778 | 0.99 | EPHX1 (0.46) | EPHX1DPP8DPP9DPP7MEN1 | |
| SCHEMBL8341764 | 0.91 | NPY4R (0.47) | EPHX1DPP8DPP9DPP7MEN1 | |
| SCHEMBL27352129 | 0.91 | NPY4R (0.47) | EPHX1DPP8DPP9DPP7MEN1 | |
| Dl-Phenylalanine SCHEMBL20580864 | 0.91 | LTA4H (0.43) | EPHX1LTA4HSLC1A3SLC1A2SLC1A1 | |
| Phenylalanine SCHEMBL18953085 | 0.91 | LTA4H (0.43) | EPHX1LTA4HSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL9490109 | 0.90 | TERT (0.51) | EPHX1DPP8DPP9DPP7MEN1 | |
| SCHEMBL8338954 | 0.87 | NPY4R (0.46) | EPHX1DPP8DPP9DPP7LTA4H | |
| SCHEMBL13437223 | 0.85 | EPHX1 (0.47) | EPHX1MEN1KMT2AMAPTPOLB | |
| SCHEMBL8768680 | 0.85 | LTA4H (0.47) | EPHX1POLBRAB9ASMN1; SMN2LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0165905-B1 | DIAGNOSTIC ASSAY METHOD FOR THE DETECTION OF ORAL PATHOGENIC BACTERIA MIXTURES | THE BOARD OF REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1989-03-08 | — | — | EP | claimed |
| US-4603108-A | Method for identification of bacterial species | NATIONAL RESEARCH DEVELOPMENT CORP. (GB) | 1986-07-29 | — | — | US | claimed |
| EP-0165905-A1 | Diagnostic assay method for the detection of oral pathogenic bacteria mixtures | THE BOARD OF REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1985-12-27 | — | — | EP | claimed |
| EP-0018825-B1 | A PROCESS FOR THE IDENTIFICATION OF BACTERIA AND A KIT OF REAGENTS FOR USE IN THIS PROCESS | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1985-02-13 | — | — | EP | claimed |
| US-4208480-A | Method, reagents and apparatus for the rapid identification of Neisseria gonorrhoeae and Neisseria meningitidis | AMERICAN HOME PRODUCTS CORPORATION (US) | 1980-06-17 | — | — | US | claimed |
| US-12377079-B2 | Antibacterial compounds and uses thereof | THE CHILDREN'S MEDICAL CENTER CORPORATION | 2025-08-05 | — | — | US | disclosed |
| CN-119875841-A | Microalgae culture method | 中国石油化工股份有限公司 | 2025-04-25 | — | — | CN | disclosed |
| WO-2023088470-A1 | PROBIOTIC COMPOSITIONS FOR TREATMENT OF HAIR LOSS | THE CHINESE UNIVERSITY OF HONG KONG (CN) | 2023-05-25 | — | — | WO | disclosed |
| US-20220023270-A1 | ANTIBACTERIAL COMPOUNDS AND USES THEREOF | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2022-01-27 | — | — | US | disclosed |
| US-10760112-B2 | Enzymatic activity assays for glucocerebrosidase | SHIRE HUMAN GENETIC THERAPIES, INC. (US) | 2020-09-01 | — | — | US | disclosed |
| CN-107751089-A | It is a kind of that the method for resisting general resistance Acinetobacter bauamnnii medicine is screened using Caenorhabditis elegans | 广州军区广州总医院 | 2018-03-06 | — | — | CN | disclosed |
| US-20180051315-A1 | ENZYMATIC ACTIVITY ASSAYS FOR GLUCOCEREBROSIDASE | SHIRE HUMAN GENETIC THERAPIES, INC. (US) | 2018-02-22 | — | — | US | disclosed |
| EP-0018825-A1 | A process for the identification of bacteria and a kit of reagents for use in this process | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1980-11-12 | — | — | EP | disclosed |
| US-4208480-A | Method, reagents and apparatus for the rapid identification of Neisseria gonorrhoeae and Neisseria meningitidis | AMERICAN HOME PRODUCTS CORPORATION (US) | 1980-06-17 | — | — | US | disclosed |
| US-4208480-A | Method, reagents and apparatus for the rapid identification of Neisseria gonorrhoeae and Neisseria meningitidis | AMERICAN HOME PRODUCTS CORPORATION (US) | 1980-06-17 | — | — | US | disclosed |
| US-4189604-A | PEPTIDASE ENZYME INHIBITORS | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1980-02-19 | — | — | US | disclosed |
| US-4185156-A | 3-AMINO-2-HYDROXY-4-PHENYLBUTANOYLARGENINE, ENZYME INHIBITORS, ANTICANCER AGENTS | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1980-01-22 | — | — | US | disclosed |
| US-4179573-A | (2S,3R)-3-amino-2-hydroxy-4-phenylbutanoic acid | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1979-12-18 | — | — | US | disclosed |
| US-4052449-A | BIOLOGICALLY ACTIVE SUBSTANCE, BESTATIN, AND PRODUCTION THEREOF | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JA) | 1977-10-04 | — | — | US | disclosed |
| US-4029547-A | Biologically active substance, bestatin, and production thereof | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JA) | 1977-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12377079-B2 | Antibacterial compounds and uses thereof | CLPP, SPOUT1, MRPL21 | EPHX1 3423/4885DPP8 142/4885DPP9 76/4885 |
| US-20220023270-A1 | ANTIBACTERIAL COMPOUNDS AND USES THEREOF | CLPP, SPOUT1, MRPL21 | EPHX1 3423/4885DPP8 142/4885DPP9 76/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.