Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.35 |
| ▸ | CHRNA2 | Q15822 | 2/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 12/20 | 0.33 |
| ▸ | APP | P05067 | 2/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
| ▸ | PIKFYVE | Q9Y2I7 | 2/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.31 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.31 |
| ▸ | REN | P00797 | 1/20 | 0.30 |
| ▸ | CTSD | P07339 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25859156 | 0.84 | CHRNB2 (0.37) | CHRNB2CHRNA2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL31496024 | 0.84 | CACNA2D1 (0.31) | CACNA2D1 | |
| SCHEMBL25863128 | 0.79 | CHRNB2 (0.36) | CHRNB2CHRNA2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL25859817 | 0.78 | — | — | |
| SCHEMBL25303044 | 0.77 | IL1B (0.53) | — | |
| SCHEMBL25303047 | 0.77 | IL1B (0.53) | — | |
| SCHEMBL25861833 | 0.77 | MEN1 (0.31) | CACNA2D1 | |
| SCHEMBL31314084 | 0.76 | ALDH1A1 (0.39) | CACNA2D1 | |
| SCHEMBL25859343 | 0.76 | ALDH1A1 (0.39) | CACNA2D1 | |
| SCHEMBL31314309 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131277-A1 | NLRP3 INFLAMMASOME INHIBITOR AND USES THEREOF | 药捷安康(南京)科技股份有限公司 | 2023-07-13 | — | — | WO | disclosed |