Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28818287 | 0.88 | LMNA (0.35) | ALDH1A1ALOX15CYP3A4TSHRTDP1 | |
| SCHEMBL20122618 | 0.86 | ALDH1A1 (0.42) | ALDH1A1ALOX15CYP3A4TSHRTDP1 | |
| SCHEMBL331957 | 0.84 | CYP3A4 (0.38) | ALDH1A1ALOX15CYP3A4TSHRTDP1 | |
| SCHEMBL28008593 | 0.83 | ACHE (0.35) | TSHRLMNA | |
| SCHEMBL28008585 | 0.82 | LMNA (0.32) | ALDH1A1ALOX15CYP3A4TSHRTDP1 | |
| SCHEMBL21562588 | 0.78 | ALDH1A1 (0.37) | ALDH1A1ALOX15CYP3A4TSHRTDP1 | |
| SCHEMBL6060005 | 0.78 | ALDH1A1 (0.37) | ALDH1A1ALOX15CYP3A4TSHRTDP1 | |
| SCHEMBL4421264 | 0.75 | ALDH1A1 (0.43) | ALDH1A1ALOX15CYP3A4TSHRTDP1 | |
| SCHEMBL5892273 | 0.74 | CYP3A4 (0.40) | ALDH1A1CYP3A4TSHRHSD17B10CYP2C19 | |
| SCHEMBL12631725 | 0.74 | ALDH1A1 (0.34) | ALDH1A1ALOX15CYP3A4TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230234922-A1 | PROCESSES FOR THE PREPARATION OF 4,6,7-TRIFLUORO-1H-INDOLE-2-CARBOXYLIC ACID | ENANTA PHARMACEUTICALS, INC. | 2023-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230234922-A1 | PROCESSES FOR THE PREPARATION OF 4,6,7-TRIFLUORO-1H-INDOLE-2-CARBOXYLIC ACID | ACE2, HTR3C, SARS1 | ALDH1A1 1129/4885ALOX15 1967/4885CYP3A4 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.