Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 1/20 | 0.49 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SCN1A | P35498 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3234717 | 0.88 | NOTUM (0.56) | KDM4EALDH1A1HPGDHTTKMT2A | |
| SCHEMBL25860219 | 0.87 | HSD17B2 (0.52) | HSD17B2KDM4EALDH1A1HPGDCA12 | |
| SCHEMBL13434198 | 0.84 | MRGPRX4 (0.49) | KDM4EALDH1A1HPGDHTTKMT2A | |
| SCHEMBL24214083 | 0.82 | NOTUM (0.57) | KDM4EALDH1A1HPGDHTTKMT2A | |
| SCHEMBL27101323 | 0.81 | HSD17B2 (0.52) | HSD17B2PTGER4KDM4EALDH1A1CA12 | |
| SCHEMBL13461275 | 0.81 | HSD17B2 (0.52) | HSD17B2PTGER4KDM4EHPGDCA12 | |
| SCHEMBL25864576 | 0.81 | PTGER4 (0.51) | HSD17B2PTGER4ALDH1A1HTTKMT2A | |
| SCHEMBL25048670 | 0.78 | CA12 (0.66) | HSD17B2KDM4EALDH1A1HPGDCA12 | |
| SCHEMBL1993657 | 0.78 | CA12 (0.56) | HSD17B2KDM4EALDH1A1HPGDHTT | |
| SCHEMBL24214079 | 0.78 | HTT (0.51) | KDM4EALDH1A1HPGDHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11702391-B2 | Inhibitors of NLRP3 inflammasome | BioAge Labs, Inc. (US) | 2023-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11702391-B2 | Inhibitors of NLRP3 inflammasome | NLRP3, CASP1, PYCARD | HSD17B2 1940/4885PTGER4 2406/4885KDM4E 3469/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.