Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | ACP1 | P24666 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12177132 | 0.88 | ALDH1A1 (0.50) | ALDH1A1ENPP2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12177164 | 0.87 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL12177341 | 0.86 | AKR1B1 (0.58) | ALDH1A1ENPP2MEN1KMT2ANPC1 | |
| SCHEMBL12177496 | 0.81 | MEN1 (0.69) | ALDH1A1ENPP2POLBMEN1KMT2A | |
| SCHEMBL12177303 | 0.80 | ENPP2 (0.55) | ENPP2PTPN1ACP1 | |
| SCHEMBL12177715 | 0.78 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL12177578 | 0.78 | ALDH1A1 (0.53) | ALDH1A1POLBMEN1KMT2AL3MBTL1 | |
| SCHEMBL12177361 | 0.77 | ENPP2 (0.46) | ALDH1A1ENPP2POLBMEN1KMT2A | |
| SCHEMBL12177581 | 0.75 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL12177447 | 0.75 | PTPN22 (0.55) | ALDH1A1ENPP2SMN1; SMN2PTPN1ACP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011135303-A2 | UBIQUITINATION MODULATORS | ITI SCOTLAND LIMITED (GB) | 2011-11-03 | — | — | WO | disclosed |
| WO-2011135303-A2 | UBIQUITINATION MODULATORS | ITI SCOTLAND LIMITED (GB) | 2011-11-03 | — | — | WO | disclosed |