Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XPO1 | O14980 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4514524 | 0.72 | XPO1 (0.36) | XPO1ALDH1A1TDP1LMNACYP3A4 | |
| SCHEMBL4506176 | 0.72 | XPO1 (0.36) | XPO1ALDH1A1TDP1LMNACYP3A4 | |
| SCHEMBL2586542 | 0.68 | DPP4 (0.34) | XPO1ALDH1A1TDP1RIPK1L3MBTL1 | |
| SCHEMBL2587429 | 0.66 | TDP1 (0.34) | XPO1ALDH1A1TDP1LMNAMAPT | |
| SCHEMBL19224612 | 0.63 | XPO1 (0.37) | XPO1CYP3A4MAPTMAPK1 | |
| SCHEMBL9889446 | 0.62 | CYP3A4 (0.50) | XPO1ALDH1A1CYP1A2CYP3A4GAA | |
| SCHEMBL3086685 | 0.61 | L3MBTL1 (0.38) | ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL2936109 | 0.61 | L3MBTL1 (0.38) | ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL15282398 | 0.60 | CYP3A4 (0.48) | XPO1CYP3A4MAPT | |
| SCHEMBL15282396 | 0.60 | CYP3A4 (0.48) | XPO1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8048878-B2 | Two cyclic cinnamide compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-11-01 | — | — | US | disclosed |