Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | XPO1 | O14980 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4506176 | 0.86 | XPO1 (0.36) | TDP1XPO1ALDH1A1L3MBTL1LMNA | |
| SCHEMBL4514524 | 0.86 | XPO1 (0.36) | TDP1XPO1ALDH1A1L3MBTL1LMNA | |
| SCHEMBL2581475 | 0.86 | L3MBTL1 (0.32) | TDP1XPO1ALDH1A1L3MBTL1 | |
| SCHEMBL3626367 | 0.86 | L3MBTL1 (0.32) | TDP1XPO1ALDH1A1L3MBTL1 | |
| SCHEMBL4497699 | 0.85 | MEN1 (0.32) | — | |
| SCHEMBL4497697 | 0.85 | MEN1 (0.32) | — | |
| SCHEMBL2586542 | 0.82 | DPP4 (0.34) | TDP1XPO1ALDH1A1L3MBTL1 | |
| SCHEMBL2585729 | 0.78 | FFAR2 (0.35) | — | |
| SCHEMBL2587432 | 0.78 | RIPK1 (0.33) | — | |
| SCHEMBL2587436 | 0.78 | RIPK1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8048878-B2 | Two cyclic cinnamide compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-11-01 | — | — | US | disclosed |