Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | XPO1 | O14980 | 2/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4514524 | 0.86 | XPO1 (0.36) | DPP4XPO1TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL4506176 | 0.86 | XPO1 (0.36) | DPP4XPO1TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL2587429 | 0.82 | TDP1 (0.34) | XPO1TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL2583332 | 0.77 | RIPK1 (0.37) | DPP4RIPK1CHRM1CHRM2CHRM3 | |
| SCHEMBL24739173 | 0.77 | CHRM1 (0.38) | TDP1L3MBTL1ALDH1A1CHRM1CHRM2 | |
| SCHEMBL2583441 | 0.76 | DPP4 (0.38) | DPP4RIPK1GPR119CHRM1CHRM2 | |
| SCHEMBL2588658 | 0.76 | NTRK1 (0.38) | GPR119ATMNTRK1 | |
| SCHEMBL2584159 | 0.74 | DPP4 (0.36) | DPP4GPR119ALDH1A1CHRM1CHRM2 | |
| SCHEMBL2584042 | 0.74 | NTRK1 (0.45) | GPR119JAK2NTRK1 | |
| SCHEMBL2584569 | 0.73 | FFAR2 (0.39) | DPP4RIPK1GPR119ALDH1A1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8048878-B2 | Two cyclic cinnamide compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-11-01 | — | — | US | disclosed |