Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 4/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7789904 | 0.88 | PPARG (0.35) | LMNAMEN1MAPTKMT2APPARG | |
| SCHEMBL28794754 | 0.85 | ALDH1A1 (0.47) | LMNAPPARGRXRA | |
| SCHEMBL7032828 | 0.83 | NR4A1 (0.35) | LMNABRD4PPARG | |
| SCHEMBL17853664 | 0.82 | PPARG (0.36) | LMNAMEN1CYP1A2MAPTCYP2C9 | |
| SCHEMBL3862066 | 0.82 | PPARG (0.36) | CYP1A2MAPTCYP2C9KMT2APPARG | |
| SCHEMBL2594098 | 0.76 | NQO2 (0.42) | LMNAMEN1CYP1A2MAPTCYP2C9 | |
| SCHEMBL24821194 | 0.75 | KDM4C (0.45) | LMNAMEN1CYP1A2MAPTCYP2C9 | |
| SCHEMBL31288115 | 0.74 | PPARG (0.49) | LMNAMEN1CYP1A2MAPTCYP2C9 | |
| SCHEMBL5712303 | 0.74 | HTR2A (0.36) | PPARGRXRA | |
| SCHEMBL11665044 | 0.73 | ACHE (0.36) | CYP1A2MAPTNPSR1PPARGMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2571497-A2 | METHODS AND COMPOSITIONS RELATED TO A RETINOID RECEPTOR-SELECTIVE PATHWAY | Sanford-Burnham Medical Research Institute (US) | 2013-03-27 | — | — | EP | claimed |
| CN-103002887-A | Methods and compositions relating to retinoid receptor selective pathways | SANFORD BURNHAM MED RES INST | 2013-03-27 | — | — | CN | claimed |
| WO-2011140525-A2 | METHODS AND COMPOSITIONS RELATED TO A RETINOID RECEPTOR-SELECTIVE PATHWAY | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2011-11-10 | — | — | WO | claimed |
| CN-102030642-A | Synthesis method and application of intermediate of sulindac analogue | UNIV XIAMEN | 2011-04-27 | — | — | CN | claimed |
| EP-3978473-B1 | COMPOUND CONTAINING AN INDOLEACETIC ACID CORE STRUCTURE AND USE THEREOF | BEIJING AN JIAN XI BIO MEDICAL TECH CO LTD (CN) | 2026-05-06 | — | — | EP | disclosed |
| EP-3978473-A1 | COMPOUND CONTAINING AN INDOLEACETIC ACID CORE STRUCTURE AND USE THEREOF | Beijing An Jian Xi Bio-Medical Technology Co., Ltd (CN) | 2022-04-06 | — | — | EP | disclosed |
| EP-3252039-B1 | COMPOUND CONTAINING INDOLEACETIC ACID CORE STRUCTURE AND USE THEREOF | BEIJING AN JIAN XI BIO MEDICAL TECH CO LTD (CN) | 2021-11-03 | — | — | EP | disclosed |
| CN-107050007-B | Methods and compositions relating to retinoid receptor selective pathways | 桑福德 - 伯纳姆医学研究所 | 2020-06-30 | — | — | CN | disclosed |
| US-10087156-B2 | Methods and compositions related to retinoid receptor-selective pathway | Sanford Burnham Prebys Medical Discovery Institute (US) | 2018-10-02 | — | — | US | disclosed |
| EP-2571497-B1 | METHODS AND COMPOSITIONS RELATED TO A RETINOID RECEPTOR-SELECTIVE PATHWAY | SANFORD BURNHAM MED RES INST (US) | 2018-09-19 | — | — | EP | disclosed |
| US-20180022700-A1 | COMPOUND CONTAINING INDOLEACETIC ACID CORE STRUCTURE AND USE THEREOF | BEIJING AN JIAN XI BIO-MEDICAL TECHNOLOGY CO., LTD. (CN) | 2018-01-25 | — | — | US | disclosed |
| EP-3252039-A1 | COMPOUND CONTAINING INDOLEACETIC ACID CORE STRUCTURE AND USE THEREOF | Beijing An Jian Xi Bio-Medical Technology Co., Ltd (CN) | 2017-12-06 | — | — | EP | disclosed |
| US-9611235-B2 | Methods and compositions related to a retinoid receptor-selective pathway | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2017-04-04 | — | — | US | disclosed |
| US-9611235-B2 | Methods and compositions related to a retinoid receptor-selective pathway | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2017-04-04 | — | — | US | disclosed |
| US-20150266842-A1 | METHODS AND COMPOSITIONS RELATED TO A RETINOID RECEPTOR-SELECTIVE PATHWAY | US ARMY, SECRETARY OF THE ARMY | 2015-09-24 | — | — | US | disclosed |
| EP-2571497-A2 | METHODS AND COMPOSITIONS RELATED TO A RETINOID RECEPTOR-SELECTIVE PATHWAY | Sanford-Burnham Medical Research Institute (US) | 2013-03-27 | — | — | EP | disclosed |
| CN-103002887-A | Methods and compositions relating to retinoid receptor selective pathways | SANFORD BURNHAM MED RES INST | 2013-03-27 | — | — | CN | disclosed |
| WO-2011140525-A2 | METHODS AND COMPOSITIONS RELATED TO A RETINOID RECEPTOR-SELECTIVE PATHWAY | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2011-11-10 | — | — | WO | disclosed |
| WO-2011140525-A2 | METHODS AND COMPOSITIONS RELATED TO A RETINOID RECEPTOR-SELECTIVE PATHWAY | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2011-11-10 | — | — | WO | disclosed |
| CN-102030642-A | Synthesis method and application of intermediate of sulindac analogue | UNIV XIAMEN | 2011-04-27 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180022700-A1 | COMPOUND CONTAINING INDOLEACETIC ACID CORE STRUCTURE AND USE THEREOF | IDO1, TPH1, IDO2 | LMNA 2460/4885MEN1 69/4885CYP1A2 399/4885 |
| US-10087156-B2 | Methods and compositions related to retinoid receptor-selective pathway | RXRG, RXRB, RXRA | LMNA 1345/4885MEN1 4249/4885CYP1A2 3693/4885 |
| US-20150266842-A1 | METHODS AND COMPOSITIONS RELATED TO A RETINOID RECEPTOR-SELECTIVE PATHWAY | RXRG, RXRB, RXRA | LMNA 1244/4885MEN1 4800/4885CYP1A2 2827/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.