Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17586458 | 0.92 | OPRD1 (0.39) | CHRNA7OPRD1SIGMAR1AVPR1A | |
| SCHEMBL25866229 | 0.88 | BRD4 (0.34) | OPRD1 | |
| SCHEMBL11832872 | 0.80 | SIGMAR1 (0.50) | SIGMAR1AVPR1A | |
| SCHEMBL31515349 | 0.79 | KDM1A (0.40) | OPRD1SIGMAR1 | |
| SCHEMBL12164932 | 0.77 | SLC6A4 (0.39) | — | |
| SCHEMBL30954699 | 0.76 | KDM1A (0.38) | OPRD1SIGMAR1 | |
| SCHEMBL11834433 | 0.74 | AVPR1A (0.45) | SIGMAR1AVPR1A | |
| SCHEMBL17586457 | 0.73 | NPY5R (0.44) | OPRD1SIGMAR1AVPR1A | |
| SCHEMBL17586442 | 0.73 | CTSC (0.40) | OPRD1SIGMAR1 | |
| SCHEMBL30954718 | 0.73 | LMNA (0.41) | OPRD1AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023134656-A1 | PEPTIDYL NITRILE COMPOUND AND USE THEREOF | 上海壹典医药科技开发有限公司 | 2023-07-20 | — | — | WO | disclosed |