Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25866229 | 0.84 | BRD4 (0.34) | BRD4PKMBACE1MAPTTP53 | |
| SCHEMBL12164932 | 0.76 | SLC6A4 (0.39) | BRD4 | |
| SCHEMBL25867739 | 0.73 | CHRNA7 (0.35) | — | |
| SCHEMBL17586458 | 0.70 | OPRD1 (0.39) | — | |
| SCHEMBL17586456 | 0.68 | OPRM1 (0.40) | BRD4BACE1KMT2AALDH1A1 | |
| SCHEMBL25866296 | 0.65 | BACE1 (0.37) | BACE1MAPTKDM1A | |
| SCHEMBL30954745 | 0.65 | OPRD1 (0.42) | MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL31515349 | 0.64 | KDM1A (0.40) | MAPTKDM1A | |
| SCHEMBL30954703 | 0.62 | BACE1 (0.34) | BACE1 | |
| SCHEMBL24988726 | 0.61 | SLC6A2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116332937-A | Dipeptidyl peptidase I inhibitors and uses thereof | 杭州邦顺制药有限公司 | 2023-06-27 | — | — | CN | disclosed |