Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 2/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14907285 | 0.86 | MEN1 (0.40) | MEN1KMT2ANPSR1RAB9ACYP3A4 | |
| SCHEMBL8736767 | 0.83 | MEN1 (0.43) | MEN1KMT2ANPSR1RAB9ACYP3A4 | |
| SCHEMBL8706596 | 0.83 | MEN1 (0.38) | MEN1KMT2ANPSR1RAB9ACYP3A4 | |
| SCHEMBL7022745 | 0.82 | CTSL (0.39) | MEN1KMT2ANPSR1RAB9ACYP3A4 | |
| SCHEMBL29024419 | 0.81 | TP53 (0.42) | MEN1KMT2ANPSR1RAB9ACYP3A4 | |
| SCHEMBL13499619 | 0.81 | L3MBTL1 (0.46) | MEN1KMT2ANPSR1L3MBTL1TDP1 | |
| SCHEMBL19512665 | 0.81 | BRD4 (0.39) | MEN1KMT2ABRD4PAX8ALDH1A1 | |
| SCHEMBL504005 | 0.79 | L3MBTL1 (0.55) | MEN1KMT2ANPSR1RAB9ACYP3A4 | |
| SCHEMBL18051150 | 0.79 | L3MBTL1 (0.54) | MEN1KMT2ANPSR1CYP3A4CYP2C9 | |
| SCHEMBL3780747 | 0.79 | MEN1 (0.40) | MEN1KMT2ANPSR1RAB9ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023134608-A1 | FUSED RING COMPOUNDS SERVING AS HPK1 INHIBITORS | 微境生物医药科技(上海)有限公司 | 2023-07-20 | — | — | WO | disclosed |