SCHEMBL2588036

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2578819	0.93	PDE4A (0.42)	METKDRPDE4APDE4BPDE4C
	SCHEMBL2580285	0.92	TSHR (0.43)	METKDRSMN1; SMN2SIRT3MEN1
	SCHEMBL2588182	0.87	FFAR4 (0.52)	METKDRFFAR1FFAR4L3MBTL1
	SCHEMBL2588042	0.87	TSHR (0.39)	METKDRFFAR1FFAR4SMN1; SMN2
	SCHEMBL2492033	0.85	MET (0.41)	METKDRFFAR1FFAR4MAPT
	SCHEMBL2586698	0.85	FFAR4 (0.42)	METKDRFFAR1FFAR4SMN1; SMN2
	SCHEMBL2580305	0.84	MAPT (0.37)	METKDRPDE4APDE4BPDE4C
	SCHEMBL2588063	0.84	ALDH1A1 (0.44)	METKDRKMT2AALDH1A1
	SCHEMBL1136343	0.82	FFAR4 (0.40)	METKDRFFAR1FFAR4MAPT
	SCHEMBL2586505	0.82	FFAR1 (0.41)	FFAR1FFAR4MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.