Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 6/20 | 0.33 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.32 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.32 |
| ▸ | ITGAL | P20701 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25869379 | 0.87 | TGFBR1 (0.35) | TGFBR1 | |
| SCHEMBL25130973 | 0.84 | TGFBR1 (0.38) | TGFBR1ITGB2ICAM1ITGALCYP3A4 | |
| SCHEMBL25130851 | 0.84 | TGFBR1 (0.38) | TGFBR1ITGB2ICAM1ITGALCYP3A4 | |
| SCHEMBL25131855 | 0.84 | TGFBR1 (0.38) | TGFBR1ITGB2ICAM1ITGALCYP3A4 | |
| SCHEMBL25310289 | 0.82 | LMNA (0.41) | TGFBR1ITGB2ICAM1ITGALCYP3A4 | |
| SCHEMBL30499627 | 0.82 | LMNA (0.41) | TGFBR1ITGB2ICAM1ITGALCYP3A4 | |
| SCHEMBL25869192 | 0.82 | WNT3A (0.37) | TGFBR1 | |
| SCHEMBL25131800 | 0.81 | TGFBR1 (0.36) | TGFBR1ITGB2ICAM1ITGALCYP3A4 | |
| SCHEMBL25131253 | 0.81 | ITGB2 (0.36) | TGFBR1ITGB2ICAM1ITGALCYP3A4 | |
| SCHEMBL25130826 | 0.81 | TGFBR1 (0.37) | TGFBR1ITGB2ICAM1ITGALCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023135107-A1 | PYRIDAZINYL AMINO DERIVATIVES AS ALK5 INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2023-07-20 | — | — | WO | disclosed |